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When to Initiate HBV Treatment Overview

About this Lesson

Last Updated: November 15th, 2025
CNE/CME

Continuing Education

This lesson qualifies for:
  • 1.0 CME AMA PRA Category 1 Credit™, or
  • 1.0 CNE contact hour and 1.0 CE contact hour (qualifies for pharmacology CE for advanced practice nurses)

CNE and CME Origination: February 15th, 2020
CNE and CME Review: December 1st, 2025
CNE and CME Expiration: November 30th, 2027 (3rd Edition)

View CE Notices

Steps to acquire a Certificate for this Lesson:

1

Study the Material

Review all Topics
2

Take the Quiz

Score 80% on 5 questions
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Complete survey
4

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Document work

3rd Edition

This is a substantial revision of the original Lesson. The previous edition was titled When to Initiate HBV Treatment and available until December 1st, 2025.

Learning Objectives

  • Identify and achieve primary goals of therapy for the treatment of chronic HBV infection
  • List three key factors to consider when initiating treatment for chronic HBV infection
  • Recognize the four phases of immune responses that can occur with HBV infection
  • Evaluate liver disease severity using noninvasive testing methods
  • Initiate HBV treatment based on key recommendations in major guidance documents

Lesson Contributors

Authors

H. Nina Kim, MD, MSc
H. Nina Kim, MD, MSc
Associate Editor
Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None
Maria A. Corcorran, MD, MPH
Maria A. Corcorran, MD, MPH
Associate Editor
Assistant Professor
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None

Reviewers

David H. Spach, MD
David H. Spach, MD
Editor-in-Chief
Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None

Lesson Plan

1Topic 1 Background

2Topic 2 Goals of Therapy with Treatment of Chronic HBV

3Topic 3 Factors Used to Determine Whether to Initiate Treatment

4Topic 4 Hepatitis B Treatment Guidance Recommendations

5Topic 5 Special Indications for Initiating Treatment

6Topic 6 Summary Points

Lesson Quiz
When to Initiate HBV Treatment Quiz

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PDF version also available.

CDC-RFA-PS21-2105

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