Hepatitis B Management:
Guidance for the Primary Care Provider
This updated 2025 guidance offers practical recommendations for the prevention, diagnosis, and management of hepatitis B—aimed specifically for primary care providers and non-specialists. Developed by the HBV Primary Care Workgroup, it builds on the original 2020 guidance with simplified, up-to-date information to support clinical decision-making.
About this Guidance
The purpose of this document is to provide simplified, up-to-date, and readily accessible guidance for primary care medical providers and non-specialists related to the prevention, diagnosis, and management of hepatitis B virus (HBV) infection, including hepatocellular carcinoma surveillance.
About the HBV Primary Care Workgroup
This guidance was developed by the Hepatitis B Primary Care Workgroup, a multidisciplinary panel of national experts in the field of viral hepatitis B, including representation from primary care, hepatology, infectious diseases, public health, and community coalitions. The workgroup did not receive any outside funding for this project.
Collaboration with University of Washington
This guidance was produced in collaboration with the University of Washington (UW) Infectious Diseases Education & Assessment (IDEA) Program. The UW IDEA program will host the most current version of this guidance on the free Hepatitis B Online website (hepatitisB.uw.edu). The Hepatitis B Online website is funded by the Centers for Disease Control and Prevention (CDC).
HBV Primary Care Workgroup Members
STEERING COMMITTEE
Amy S. Tang, MD
Su Wang, MD, MPH
Karla Thornton, MD, MPH
H. Nina Kim, MD, MSc
David H. Spach, MD
Workgroup Members (listed in alphabetical order)
Richard Andrews, MD, MPH
Carla S. Coffin, MD, MSc
Chari Cohen, DrPH, MPH
Jordan Feld, MD, MPH
Jean-Jacques Kayembe, MD, MPH
Min Kim, MD
Joseph K. Lim, MD
Ronald Nahass, MD, MHCM
Thaddeus Pham, MPH
Nancy Reau, MD
Richard So, MPH, MPA
Norah A. Terrault, MD, MPH
Amy Trang, PhD, M.Ed
Carolyn Wester, MD, MPH
Nash A.K. Witten, MD
Robert J. Wong, MD, MS
Julie Yoshimachi, DNP
Workgroup Support
Zinnia Dong
Suggested citation. Tang AS, Wang S, Thornton K, and HBV Primary Care Workgroup. Hepatitis B Management: Guidance for the Primary Care Provider. December 1, 2025. [https://www.hepatitisB.uw.edu/hbv-pcw/guidance]
